Name	Isosorbide
Description	Isosorbide (Devicoran) is a heterocyclic compound that is derived from glucose, used as a diuretic.
In vitro	Isosorbide increases urine volume by increasing the amount of osmotically active solute in the urine. Osmotic diuretics also increase the osmolarity of plasma. Isosorbide is used to prevent or treat chest pain (angina). It works by relaxing the blood vessels to the heart, so the blood and oxygen supply to the heart is increased. [1]
Storage	Pure form: -20°C for 3 years \| In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	10% DMSO+90% Saline : 10 mg/mL (68.43 mM), Solution. DMSO : 237.5 mg/mL (1625.15 mM), Sonication is recommended. H2O : 100 mg/mL (684.28 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (13.69 mM), Sonication is recommended.
Keywords	vasodilating \| pain \| Isosorbide \| Inhibitor \| inhibit \| hyperosmotic \| heart \| failure \| diuretic \| chest \| angina
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