1. Materials information
Names
| Name | Isoflupredone Acetate |
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| Synonym | More Synonyms |
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Predef Biological Activity
| Description | Isoflupredone acetate is a corticosteroids with anti-inflammatory activity. Isoflupredone acetate can be used for research ketosis, musculoskeletal disorders, hypersensitivity, infections, inflammatory diseases in cows, horse, pigs, et al.[1][2]. |
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| Related Catalog | Research Areas >> Infection Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology |
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| In Vitro | Isoflupredone acetate (10-4, 10-7, or 10-10 M; 48 or 96 h)mitigates the inflammatory and catabolic effects of IL-1β in synovial and osteochondral explants (from equine cadavers) to a greater extent in low concentrations (10-7 M and 10-10 M) than the high concentration (10-4 M)[1]. |
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| In Vivo | Isoflupredone acetate (0.05 mg/kg; i.m.; on days 2 and 4 after the challenge) prevents dry-matter intake and average daily gain reductions, and leads to faster Mannheimia haemolytica-infected clinical improvement when co-treated with Oxytetracycline (HY-B0275)[2]. Animal Model: 96 weanling heifers (Bronchopneumonia was induced by intrabronchial infusion of Mannheimia haemolytica)[2] Dosage: 0.05 mg/kg Administration: i.m.; on days 2 and 4 after the challenge Result: Infection caused a reduction in dry-matter intake and average daily gain (ADG) in heifers.Prevented these reductions and resulted in faster clinical improvement when co-treated with Oxytetracycline (HY-B0275). |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 576.5±50.0 °C at 760 mmHg |
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| Melting Point | 244-246 °C |
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| Molecular Formula | C23H29FO6 |
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| Molecular Weight | 420.471 |
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| Flash Point | 302.5±30.1 °C |
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| Exact Mass | 420.194824 |
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| PSA | 100.90000 |
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| LogP | 2.46 |
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| Vapour Pressure | 0.0±3.6 mmHg at 25°C |
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| Index of Refraction | 1.577 |
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| Storage condition | -20°C |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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