| Name | Iriflophenone |
| Description | Iriflophenone stimulates cells proliferation in MCF-7 and T-47D human breast cancer. |
| In vitro | 2,2'-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity was used to evaluate the antioxidant capacity of the CPE. Experimental results concluded that ethanol concentration and solid-to-solvent ratio had significant effects (p<0.05) on the yields of polyphenol and antioxidant capacity. Extraction time had an insignificant influence on the recovery of EGCG, ECG and Iriflophenone 3-C-β-glucoside, as well as radical scavenging capacity from the CPE. The extraction parameters that exhibited maximum yields were 40% (v/v) ethanol, 1:60 (w/v) for 30 min where the TPC, TFC, TF, DPPH, EGCG, ECG and Iriflophenone 3-C-β-glucoside levels achieved were 183.5 mg GAE/g DW, 249.0 mg QE/g DW, 4.9 mg CE/g DW, 93.7%, 29.1 mg EGCG/g DW, 44.3 mg ECG/g DW and 39.9 mg Iriflophenone 3-C-β-glucoside/g DW respectively. The IC50 of the CPE was 24.6 mg/L. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 60 mg/mL (243.68 mM), Sonication is recommended.
|
| Keywords | T-47D | proliferation | progestogenReceptor | progestogen Receptor | MCF-7 | Iriflophenone | Inhibitor | inhibit | EstrogenReceptor | Estrogen/progestogen Receptor | Estrogen Receptor/ERR | Estrogen Receptor | ERR | cells |
| Inhibitors Related | Tamoxifen | Mifepristone | Estradiol | Astragaloside IV | Estradiol benzoate | Bisphenol B | Melatonin | Allura Red AC | 17α-Hydroxyprogesterone | Ethisterone | Ferrous Bisglycinate | Cholesterol |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Polyphenolic Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Ancient Chinese Classical Formulas Compound Library | Anti-Cancer Active Compound Library |
United States
