Hyaluronic acid is an acidic mucopolysaccharide that exhibits a variety of important physiological functions in the body, such as lubricating joints, regulating the permeability of blood vessel walls, regulating protein, water and electrolyte diffusion and operation, and promoting wound healing.
Hyaluronic acid is widely used in various ophthalmic operations, such as lens implantation, corneal transplantation and anti-glaucoma surgery. It can also be used to treat arthritis and accelerate wound healing. Used in cosmetics, it can play a unique role in protecting the skin. It can keep the skin moist, smooth, delicate, tender, and elastic. It has the functions of anti-wrinkle, anti-wrinkle, beauty care and restoration of the physiological functions of the skin.
| Item | Standard | Result |
| Appearance | White powder | White powder |
| Identification | A. Infrared absorption spectrophotometry | Complied |
| B. It gives reaction (a) of sodium |
| Solubility | Soluble in water | Complied |
| Sodium Hyaluronate | 95.0% - 105.0% | 97.1% |
| Appearance of Solution | A600nm< 0.01 | Complied |
| Nucleic Acid | A260nm< 0.5 | Complied |
| pH | 5.0 - 8.5 | 6.5 |
| Molecular Weight | 2.0 - 2.5 Million Dalton | 2.28 Million Dalton |
| Intrinsic viscosity | 2.96 - 3.52 m3/kg | 3.27 m3/kg |
| Protein | <0.01% | <0.01% |
| Loss on drying | <10% | 5.9% |
| Residue on Ignition | <20% | 15.31% |
| Chlorides | <0.5% | <0.5% |
| Heavy metal | <10ppm | <10ppm |
| Arsenic | <2ppm | <2ppm |
| Bacteria Count | <10CFU/G | Complied |
| Molds & Yeast | <10CFU/G | Complied |
| Staphylococcus aureus | Negative | Negative |
| Pseudomonas aeruginosa | Negative | Negative |
| Hemolysis | Negative | Negative |
| Viable Hemolytical Streptococci | Negative | Negative |
| Endotoxin Level | <5.0IU/mg | <5.0IU/mg |
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