1. Materials information
Names
| Name | glycerol |
|---|
| Synonym | More Synonyms |
|---|
Glycerol Biological Activity
| Description | Glycerol is a clear, colourless, viscous, sweet-tasting liquid. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis. |
|---|
| Related Catalog | Research Areas >> Inflammation/Immunology Biochemical Assay Reagents Research Areas >> Cancer Research Areas >> Cardiovascular Disease |
|---|
| Target | Human Endogenous Metabolite |
|---|
| In Vitro | Glycerol is often included in polyacrylamide gels to prevent dissociation of nucleosomes and other protein-DNA complexes during electrophoresis. With glycerol included, fractionation seems to be largely based on particle mass and charge. The concentration of glycerol during electrophoresis strongly affects the separation characteristics of polyacrylamide gels[1]. Glycerol is an inevitable by-product of oils/fats processing, regardless of the pathway. Fermentative metabolism of glycerol has been studied in great detail in several species of the Enterobacteriaceae family, such as Citrobacter freundii and Klebsiella pneumoniae. The use of anaerobic fermentation to convert abundant and low-priced glycerol streams generated in the production of biodiesel into higher value products represents a promising route to achieve economic viability in the biofuels industry[2]. |
|---|
| In Vivo | Glycerol can induce acute renal failure in rat models. Acute renal failure induced by glycerol or uranyl nitrate reduces the hepato-biliary transport of some drugs, modulates the distribution of drugs into the central nervous system and affects the activity of various hepatic microsomal enzymes [3]. |
|---|
| Animal Admin | Rats: Experimental acute renal failure was induced in male Wistar rats 230-300 g by an injection of glycerol dissolved in saline (50% v/v, 10 mL/kg) into the leg muscle after a 24-h period of water deprivation[3]. |
|---|
| References | [1]. Pennings S, et al. Effect of glycerol on the separation of nucleosomes and bent DNA in low ionic strengthpolyacrylamide gel electrophoresis. Nucleic Acids Res. 1992 Dec 25;20(24):6667-72. [2]. Yazdani SS, et al. Anaerobic fermentation of glycerol: a path to economic viability for the biofuelsindustry. Curr Opin Biotechnol. 2007 Jun;18(3):213-9. [3]. Huang ZH, et al. Expression and function of P-glycoprotein in rats with glycerol-induced acute renal failure. Eur J Pharmacol. 2000 Oct 20;406(3):453-60. |
|---|
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|
| Boiling Point | 290.0±0.0 °C at 760 mmHg |
|---|
| Melting Point | 20 °C(lit.) |
|---|
| Molecular Formula | C3H8O3 |
|---|
| Molecular Weight | 92.094 |
|---|
| Flash Point | 160.0±0.0 °C |
|---|
| Exact Mass | 92.047340 |
|---|
| PSA | 60.69000 |
|---|
| LogP | -2.32 |
|---|
| Vapour density | 3.1 (vs air) |
|---|
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
|---|
| Index of Refraction | 1.490 |
|---|
| Stability | Stable. Incompatible with perchloric acid, lead oxide, acetic anhydride, nitrobenzene, chlorine, peroxides, strong acids, strong bases. Combustible. |
|---|
| Water Solubility | >500 g/L (20 ºC) |
|---|
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 86 13526505137
China
