Antiviral drugs Ganciclovir sodium CAS:107910-75-8
| Product Name | Ganciclovir sodium |
| CAS No. | 107910-75-8 |
| Molecular Formula | C9H12N5NaO4 |
| Molecular Weight | 277.21 |
| Appearance | White Powder |
| Key words | Ganciclovir sodium;Ganciclovir sodium price; Ganciclovir sodium powder |
Ganciclovir sodium is first phosphorylated to monophosphate by the CMV-encoded (UL97 gene) protein kinase homolog and further phosphorylated to diphosphate and triphosphate by cellular kinases. In CMV-infected cells, triphosphate levels were 100-fold higher than in non-infected cells, suggesting that Ganciclovir sodium may be preferentially phosphorylated in infected cells. Ganciclovir sodium, once triphosphate formed, persists in CMV-infected cells for several days. The triphosphates of Ganciclovir sodium are thought to inhibit viral DNA synthesis by: 1. Competitively inhibiting viral DNA polymerase; 2. Co-entry into viral DNA, resulting in termination of viral DNA elongation.
Applications:
1. Immunocompromised individuals include cytomegalovirus retinitis in AIDS patients.
2. Prevention of cytomegalovirus infection that can occur in recipients of organ transplants.
| Shipping | weight | Transportation time |
| By Air | <500kg | 3-7days |
| By Sea | ≥500kg | 15-30days |
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
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