Felodipine

Used for the treatment of hypertension. It is a selective calcium antagonist that mainly inhibits the influx of extracellular calcium in arteriolar smooth muscle cells, selectively dilates arterioles, has no such effect on veins, and does not cause orthostatic hypotension; There was also no significant inhibitory effect on myocardium. This product not only reduces the resistance of renal blood vessels, but also does not affect the glomerular filtration rate and creatinine clearance rate. Renal blood flow does not change or even slightly increases, and has the effects of promoting sodium excretion and diuresis. This product can increase output and cardiac index, significantly reduce afterload, but has no significant impact on cardiac systolic function, preload, and heart rate.