Ethyl 2-chloroacetoacetate is an important intermediate for the synthesis of febuxostat. Febuxostat is a new-generation xanthine oxidase inhibitor developed by Teijin Corporation, and is clinically used for the treatment of hyperuricemia.
Specifications
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Density 1.2±0.1 g/cm3
Boiling point 225.5±0.0 °C at 760 mmHg
Melting point -80 °C
Molecular formula C6H9ClO3
Molecular weight 164.587
Flash point 50.0±0.0 °C
Exact mass 164.024017
PSA 43.37000
LogP 1.66
Appearance: Transparent bright yellow liquid
Vapor Pressure 0.1±0.4 mmHg at 25°C
Refractive index 1.434
Storage conditions
Sealed and stored in a cool place.
stability
1. Under normal temperature and pressure, or without decomposition products.
Japan
