1. Materials information
Names
| Name | ebselen |
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| Synonym | More Synonyms |
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Ebselen Biological Activity
| Description | Ebselen is a small-molecule capsid Inhibitor of HIV-1 replication.Target:Ebselen is an organoselenium compound, as an inhibitor of HIV-1 capsid CTD dimerization. Ebselen inhibits early viral postentry events of the HIV-1 life cycle by impairing the incoming capsid uncoating process. [1] Ebselen is a non-toxic seleno-organic drug with anti-inflammatory and antioxidant properties. Ebselen is an inhibitor of inositol monophosphatase (IMPase). Ebselen permeates the blood-brain barrier and inhibits endogenous inositol monophosphatase in mouse brain. [2] |
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| Related Catalog | Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> Anti-infection >> HIV Research Areas >> Inflammation/Immunology |
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| References | [1]. Thenin-Houssier S, et al. Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2195-208. [2]. Singh N, et al. A safe lithium mimetic for bipolar disorder. Nat Commun. 2013;4:1332. doi: 10.1038/ncomms2320. |
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Chemical & Physical Properties
| Boiling Point | 402.8±28.0 °C at 760 mmHg |
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| Melting Point | 178-181 °C |
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| Molecular Formula | C13H9NOSe |
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| Molecular Weight | 274.177 |
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| Flash Point | 197.4±24.0 °C |
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| Exact Mass | 274.984924 |
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| PSA | 22.00000 |
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| LogP | 2.04770 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Storage condition | 2-8°C |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
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