Manufacturer Provide Pharmaceutical Intermediate CAS117704-25-3 Veterinary Raw Material Doramectin powder
Introduction
1.Product Name:Doramectin
2.Synonym:25-CYCLOHEXYL-5-O-DEMETHYL-25-DE(1-METHYLPROPYL)AVERMECTIN
3.CAS NO: 117704-25-3
4.Purity: 99%min
5.Appearance: White crystalline powder
6.Molecular formula: C50H74O14
7.Molecular weight :899.11
8.Melting Point :116-119°C(lit.)
9.Storage Temperature :Keep in a cool, dry, dark location in a tightly Sealed in dry,Store in freezer, under -20°C
10.Packing: Bag, drum
Doramectin is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites).Doramectin is a derivative of ivermectin.Its spectrum includes:Haemonchus spp.,Ostertagia spp.,Trichostrongylusspp.,Cooperia spp.,Oesophagostomum spp.,Dictyocaulus viviparus,Dermatobia hominis,Boophilus microplus,Psoroptes bovis,among many other internal and external parasites.Doramectin is available in 2 dosage forms: as aninjection and as a 5 mg/ml topical solution.
| Items | Specification | Results |
| Appearance | White crystalline powder | pass |
| Identification | HPLC: the retention time of major peak of test solution should correspond to that of reference solution. | conform |
| IR: Sample spectrum corresponds to that of standard spectrum. | conform |
| Appearance of solution | The solution is clear and not more intensely colored than reference solution BY6. | conform |
| Related substance | Avermectin: NMT2.0% | 0.41% |
| Total impurities: NMT5.0% | 2.57% |
| Residual solvents | Ethanol:NMT30000ppm | 15500ppm |
| Acetone:NMT5000ppm | 5ppm |
| BHT | NMT2000ppm | 43ppm |
| Sulphate ash | NMT0.1% | 0.03% |
| Water | NMT3.0% | 1.6% |
| Heavy metal | NMT20ppm | 20ppm |
| Assay | ≥95.0% | 99.1% |
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