Name	Doramectin
Description	Doramectin (Dectomax) is an antiparasitic agent.
Kinase Assay	To determine which caspases are involved in apoptosis induced by taxol, caspase-3 inhibitor (DEVD-CHO), caspase-6 inhibitor (Z-VEID-FMK), caspase-8 inhibitor (Z-IETD-FMK or IETD-CHO), caspase-9 inhibitors (Z-LEHD-FMK or LEHD-CHO), and caspase-10 inhibitor (Z-AEVD-FMK) are used. These caspase inhibitors are dissolved in dimethyl sulfoxide (Me2SO); the final concentration of Me2SO is 0.1%. Cells (5×105) are preincubated in the presence or absence of 100 μM?each of these inhibitors for 3 h at 37°C then treated with or without 0.1, 0.5, and 1 μM?Paclitaxel for 48 h and processed for annexin V binding assay.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 30 mg/mL (33.37 mM)
Keywords	Doramectin \| Parasite \| Antibiotic \| Inhibitor \| inhibit
Related Compound Libraries	Anti-Parasitic Compound Library \| Bioactive Compound Library \| Natural Product Library \| Microbial Natural Product Library \| Antiparasitic Natural Product Library \| Natural Product Library for HTS \| Anti-infective Natural Product Library \| Bioactive Compounds Library Max

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Product Introduction