CHEMICAL IDENTIFICATIONCHEMICAL NAME : 2,7-Naphthalenedisulfonic acid, 3,3'-((3,3'-dimethoxy-4,4'-biphenylylene)bis(azo))bis ( 5-amino-4-hydroxy-, tetrasodium salt
CAS REGISTRY NUMBER : 2429-74-5
MOLECULAR FORMULA : C34-H24-N6-O16-S4.4Na
HEALTH HAZARD DATAACUTE TOXICITY DATASPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 52500 mg/kg/14D-C
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 10 gm/kg/13W
TOXIC EFFECTS : Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 168 gm/kg/96W-C
ROUTE OF EXPOSURE : Intraperitoneal
ROUTE OF EXPOSURE : Intraperitoneal
ROUTE OF EXPOSURE : Intraperitoneal
MUTATION DATADOSE/DURATION : 100 ug/plate
REFERENCE : JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 18,111,1986 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,235,1993 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,235,1993 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 57,235,1993 TOXICOLOGY REVIEW ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 1,131,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M4514 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 69 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M4514 No. of Facilities: 485 (estimated) No. of Industries: 7 No. of Occupations: 7 No. of Employees: 4527 (estimated) No. of Female Employees: 201 (estimated)
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