Dimethocaine Hydrochloride (CAS 553-63-9)
✦ Product Profile
Dimethocaine Hydrochloride, a synthetic local anesthetic agent with the molecular formula C₁₆H₂₆N₂O₂·ClH, is distinguished by its nerve-blocking efficacy and structural uniqueness compared to traditional anesthetics13. It is primarily employed in pharmaceutical research and preclinical applications due to its reversible inhibition of sodium channels, enabling precise neurological studies24.
✦ Core Features
🔹 Pharmaceutical-Grade Purity: ≥99% (HPLC-validated), ensuring reliability in sensitive formulations15.
🔹 Thermal Stability: Melting point 196–197°C, suitable for controlled storage and global distribution36.
🔹 Regulatory Alignment: Complies with USP42 standards, meeting stringent pharmacopeial requirements57.
✦ Primary Applications
Medical Research: Preclinical evaluation of local anesthesia mechanisms.
Neurological Studies: Signal transmission inhibition in experimental models.
Drug Development: Intermediate for novel anesthetic agents with reduced systemic toxicity.
✦ Quality Assurance
Rigorous testing via HPLC, FTIR, and mass spectrometry, supported by batch-specific Certificates of Analysis (COAs)
. Stability studies confirm compliance with ICH guidelines for long-term storage.
✦ Market Relevance
The global anesthetic market is projected to grow at 5.2% CAGR (2025–2030), driven by advancements in surgical techniques and demand for safer alternatives
. Dimethocaine Hydrochloride remains integral to R&D efforts targeting enhanced therapeutic profiles
.


