Factory Supply Dihexa CAS:1401708-83-5 With High Purity
Product Name:Dihexa
Synonyms:Dihexa;Hexanoyl-Tyr-Ile-Ahx-NH2;N-hexanoic-Try-Ile-(6)-amino hexanoic amide;PNB-0408;Dihexa (PNB-0408);N-(1-OXOHEXYL)-L-TYROSYL-N-(6-AMINO-6-OXOHEXYL)-L-ISOLEUCINAMIDE;L-Isoleucinamide, N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-;TIANFUCHEM--1401708-83-5---Dihexa
CAS:1401708-83-5
MF:C27H44N4O5
MW:504.66
EINECS:227-005-2
Melting point:>209°C (dec.)
Boiling point:866.2±65.0 °C(Predicted)
density:1.111±0.06 g/cm3(Predicted)
storage temp.:Hygroscopic, Refrigerator, under inert atmosphere
solubility:DMSO (Slightly), Methanol (Slightly)
Uses:N-Hexanoic-Try-Ile-(6)-amino Hexanoic amide (Dihexa) is an angiotensin IV analog as a procognitive/antidementia agent.
Description
Dihexa (developmental code name PNB-0408), also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.
China
