| Name | Dihexa |
| Description | Dihexa (Hexanoyl-Tyr-Ile-Ahx-NH2) is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) system,it binds to HGF (Kd = 65 pM),and an analog of the peptide angiotensin IV. |
| In vivo | Dihexa (2 mg/kg, i.p.) completely reverses scopolamine-induced learning deficits in the latency to find the platform and increases the time spent in the target quadrant in the Morris water maze in rats[1] |
| Storage | Keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% (20% SBE-β-CD in Saline) : < 10 mg/mL (19.82 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+90% Saline : < 10 mg/mL (19.82 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
10% DMSO+90% Corn oil : 10 mg/mL (19.82 mM), Solution.
DMSO : 250 mg/mL (495.38 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : < 10 mg/mL (19.82 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
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| Keywords | PNB0408 | PNB 0408 | N-hexanoic-Try-Ile-(6)-amino hexanoic Amide | HGFR | HGF | Dihexa | cMet/HGFR | c-Met | cMet |
| Inhibitors Related | (S)-Afatinib | (Z)-Semaxinib | Decanoic Acid | Afatinib Dimaleate | L-Ascorbic acid 2-phosphate trisodium | Crizotinib | 7-Methoxy-1-tetralone | Tepotinib | Afatinib | Cabozantinib S-malate | Bacitracin Zinc | Capmatinib |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Reprogramming Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Peptide Compound Library | Bioactive Compounds Library Max | Anti-COVID-19 Compound Library | Anti-Cancer Compound Library |
United States
