| Name | D-Phenylalanine |
| Description | D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine). |
| In vitro | Aspirin (oral administration of 200 mg/kg) co-administered with D-phenylalanine (oral administration of 500 mg/kg) rather than with sodium zomepirac (oral administration of 200 mg/kg) resulted in a statistically significant minor increase in the aversion threshold. The oral administration of 500 mg/kg D-Phenylalanine alone caused a minor, statistically insignificant increase in the aversion threshold that was not reversed by naloxone. |
| In vivo | D-Phenylalanine binds to carboxypeptidase A by disrupting the functional active site at Glu-270 and the hydrogen bonds between zinc-bound water molecules, facilitating the displacement of metal-bound water anions. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : Insoluble
H2O : 10 mM, Sonication is recommended.
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| Keywords | Monocarboxylatetransporter | Monocarboxylate transporter | Inhibitor | inhibit | EndogenousMetabolite | Endogenous Metabolite | D-Phenylalanine | DPhenylalanine | D Phenylalanine |
| Inhibitors Related | Sucrose | Aceglutamide | L-Pyroglutamic acid | Emtricitabine | Levulinic acid | D(+)-Raffinose pentahydrate | D-(+)-Trehalose dihydrate | Glycerol | Thymidine | Gluconate Calcium | Ovalbumins | Chitosan oligosaccharide |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Drug Repurposing Compound Library | Natural Product Library | Microbial Natural Product Library | Anti-Cancer Approved Drug Library | Natural Product Library for HTS | Bitter Compound library | Bioactive Compounds Library Max | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library | Anti-Cancer Drug Library |
United States
