| CAS: | 157-06-2 |
| MF: | C6H14N4O2 |
| MW: | 174.2 |
| EINECS: | 205-866-5 |
| Product Categories: | amino;Amino Acids;Arginine [Arg, R];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Amino Acids Derivatives;chiral;PROTECTED AMINO ACID & PEPTIDES;Biochemistry;for Resolution of Acids;Optical Resolution;Synthetic Organic Chemistry |
| Mol File: | 157-06-2.mol |
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| D(-)-Arginine Chemical Properties |
| Melting point | 226 °C (dec.) (lit.) |
| alpha | -28.5 º (c=8, 6 N HCl) |
| Boiling point | 305.18°C (rough estimate) |
| density | 1.2297 (rough estimate) |
| refractive index | -23 ° (C=8, 6mol/L HCl) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| pka | 2.49±0.24(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | SOLUBLE |
| Sensitive | Air Sensitive |
| BRN | 1725412 |
| InChIKey | ODKSFYDXXFIFQN-SCSAIBSYSA-N |
| LogP | -0.999 (est) |
| CAS DataBase Reference | 157-06-2(CAS DataBase Reference) |
| EPA Substance Registry System | D-Arginine (157-06-2) |
| D(-)-Arginine Usage And Synthesis |
| Description | D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine. |
| Chemical Properties | white to light yellow crystal powde |
| Uses | Arginine is an essential amino acid found in food and plant sources, and many biological systems.
D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man.
D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite. |
| Uses | 1-Deamino-8-D-arginine vasopressin makes a new pharmacological approach to the management of haemophilia and von Willebrand's disease. A novel nonenzymatic pathway for the generation of nitric oxide is by the reaction of hydrogen peroxide and d- or l-arginine. |
| Definition | ChEBI: A D-alpha-amino acid that is the D-isomer of arginine. |
| References | https://www.alfa.com/zh-cn/catalog/A16137/
Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993.
Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008).
Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154. |
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Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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