Manufacturer Provide Animal Antibiotics CAS 1404-26-8 Polymyxin B2/Colistin Sulphate
Introduction
Product Name: Colistin Sulphate
Other Name :belcomycin;Animal Feed Additives colistin sulfate Colistin Sulfate
CAS NO:1264-72-8
Purity: 99%min
Appearance:White powder
Molecular formula: 2(C52H98N16O13).5(H2SO4)
MW:2801.27
Melting Point :200-220°C
Solubility :Soluble in water
Storage :Keep in dark place,Inert atmosphere,Room temperature
Colistin Sulfate, also known as colistin, polymyxin E, antibiotics, etc., is a white or nearly white powder, odorless, bitter, and hygroscopic. It is easily soluble in water, slightly soluble in methanol, ethanol, and almost insoluble in acetone, ether, etc. It is also slightly soluble in water when it is free from alkali. Stable within the range of PH3-7.5. Sulfuric colistin is produced by polymyxin and has a strong antibacterial effect on Gram negative bacteria. It is used to treat intestinal diseases caused by Gram negative bacteria, as a feed additive, and has a significant growth promoting effect. It works well when combined with sulfadiazine.
| ITEMS | SPECIFICATION | RESULT |
| DESCRIPTION | WHITE OR ALMOST WHITE POWDER | WHITE POWDER |
| IDENTIFICATION | COMPLIES | COMPLIES |
PH VALUE | 4.0~6.0 | 4.6 |
LOSS ON DRYING | ≤3.5% | 1.8% |
(DRIED SUBSTANCE)
COMPOSITION | Polymyxin E1-I ≤8 .5% | 0.5% |
| Polymyxin E3:≤5.5% | 3.2% |
| Polymyxin E1-7MOA:≤5.0% | 3.7% |
| Polymyxin E6:≤4.5% | 1.0% |
| Polymyxin E1-Nva: ≤4.5% | ND |
| Polymyxin E4+E1-Va1 ≤3.0% | 2.0% |
| Polymyxin E2-I ≤2 .5% | 0.9% |
| Polymyxin2,3-dehydro E1: ≤1.5% | 0.4% |
| SUM :≥86.0% | 93.2% |
RELATED SUBSTANCES | IMPURITY B:≤4.0% | ND |
| Any impurity:≤2.5% | 1.4% |
| Not more than 4 such impurities exceed 1.0% | 4 |
| Total impurity : ≤11.0% | 6.7% |
DRIED SUBSTANCE
SULFATE | 16.0~18.0% | 17.2% |
SULFATED ASH | ≤1.0% | 0.3% |
| (DRIED BASIS)ASSAY | ≥19000IU/mg | 23883IU/mg |
| ( MOISTED BASIS) ASSAY |
| 23453IU/mg |
China
