Product Description
Coenzyme Q10 (CoQ10) is a quinone that is found throughout the human body in cell membranes, primarily in mitochondrial membranes, with the highest levels in the heart, lungs, liver, kidneys, spleen, pancreas, and adrenal glands. It exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone or ubisemiquinone), and fully reduced (ubiquinol; ). CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex. CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis. Mutations in genes encoding enzymes involved in CoQ10 biosynthesis lead to primary CoQ10 deficiency, which is characterized by encephalopathy, cerebellar ataxia, infantile multisystemic form, nephropathy, and isolated myopathy. Secondary CoQ10 deficiency, induced by non-genetic impaired CoQ10 biosynthesis, insufficient CoQ10 intake, or excessive CoQ10 utilization, has been observed in a variety of conditions, including ataxia-oculomotor-apraxia 1 (AOA1), mitochondrial diseases, and hypercholesteremia with statin therapy. Formulations containing CoQ10 have been used in the treatment of CoQ10 deficiency.
Product Name | Coenzyme Q10 |
Colour | Orange |
Density | 0.9145 |
BRN | 1729812 |
Form | Solid |
Solubility | DMSO (Very Slightly), Water (Slightly) |
Storage temp. | -20℃ |
Mol file | 303-98-0.mol |
MW | 863.34 |
Company Profile
Wuhan Hansheng New Material Technology Co. Ltd is a professional company which specialized in manufacturing and selling chemical raw materials, chemical products, pharmaceutical intermediates, veterinary medicine intermediates, dye intermediates, pigments, cosmetics raw materials and chemical reagents.
We have long term cooperation pharmaceutical raw material production plant and a reagent research and development center, with a rich professional background and strong competitive advantage. We have a professional and experienced team and we promise clients to provide the best quality, price and service. During the business cooperation with clients, we always adhere principle of Honesty, Trustworthiness and win-win policy. We guarantee 100% qualification of our products pass through the standard of USA, Mexico, UK, Australia, Canada, Brazil, France, Germany, Spain, Belgium, Sweden, the Netherlands and so on
Packing & Shipping
FAQ
1. Are you a trade company or factory?
We are a factory with our own trading company.
2. How do you control the quality?
Our factory is equipped with professional technicians to inspect the quality around production lines. The inspection test would be made every 2 hours to ensure the production conform to quality standard. We also accept BV, SGS, or any third pary inspection.
3. How long is lead time?
We deliver goods within 3 days for small order, 7-10 days for bulk order.
4. Where is your factory located? How can I visit the factory?
Our factory is located in Hebei, China
5. Can I get some samples?
Yes.
6. How to start orders or make payments?
Proforma Invoice will be issued first after confirmation of order, enclosed our bank information. Payment could be done by T/T or Western Union.
7. How to confirm the product quality before placing order?
You can get samples of all products for test before placing order .
8. How do you treat quality complaint?
First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Contact Information
Wuhan
Hansheng New Material Technology Co. Ltd
Website:
whhansheng.en.made-in-china.com
Address: Room 401, Floor 4, Plant No. 3-1, Guandong Science and Technology Industrial Park, Guandong Street, Jiayuan Road, Wuhan, Hubei, China
Contact Person: Sherry
Cheng
WhatsApp/Wechat: +86 19071429669
Email: admin02@hsnm.com.cn