[Description]
Cocamidopropyl betaine is an important zwitterionic surfactant, with a mild detergent action that is also more viscous than the other types of surfactant. |
[Definition]
Cocamidopropyl betaine, an amphoteric surfactant, is one of the most commonly used surfactants in cosmetics. It is synthesized from three substances: a coca fatty acid, dimethylaminopropylamine, and rnonochloroacetic acid. It is patch tested as a 1% concentration in water. |
[solubility ]
Methanol (Slightly), Water (Sparingly) |
[form ]
Clear Colourless Solution |
[Contact allergens]
Cocamidopropyl betaine is a pseudo-amphoteric zwitterion detergent derived from long-chain alkylbetaines. It is available from many suppliers under more than 50 trade names (including Tego-betain L7 and Ampholyt JB 130). Exposure occurs via rinse-off products such as liquid soaps, shampoos, and shower gels, but also via leave-on products (for example, roll-on deodorant). Occupational sources are mainly in hairdressing. The first synthesis step consists of the reaction of coconut fatty acids with 3-dimethylaminopropylamine, giving cocamidopropyl dimethylamine. This amido amine is converted into cocamidopropyl betaine by reaction with sodium monochloroacetate. Both dimethylaminopropylamine and cocamidopropyl dimethylamine are thought to be the sensitizers. |
[LogP]
0.326 (est) |
[Uses]
Cocamidopropyl betaine is an amphoteric surfactant, which enjoys increasing popularity among cosmetic chemists because of its low potential for irritation of the skin. It is used especially in shampoos and bath products such as bath and shower gels. Most cases of allergy are caused by shampoos . Thus, Cocamidopropyl betaine is the exception to the rule that allergic reactions arc usually caused by “stay-on” (“leave-on”) cosmetic products. However, Cocamidopropyl betaine may also be an allergen in other cosmetic products such as skin care products and deodorants and in contact lens fluids. |
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