Product Name: Cilengitide
Cas No: 188968-51-6
Formula: C27H40N8O7
Molecular:588.65
Sequence: Cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-N-methyl-L-valyl)
Purity:98%
Appearance: white powder
Source: synthetic
Cilengitide is a peptide that inhibits the integrin receptor, which may be involved in tumorigenesis. It blocks the process of cellular transformation and inhibits tumor growth by blocking angiogenesis. Cilengitide has been shown to have minimal toxicity in vitro and in vivo, which is likely due to its low solubility in water. This peptide also has antitumor activity against solid tumours and can inhibit the growth of human breast cancer cells. Cilengitide was found to be effective in an experimental model using MDA-MB-231 breast cancer cells, demonstrating its potential for use as a therapeutic agent for cancer treatment.
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