Manufacturer Provide Cibinetide Acetate Ara-290 Ara290 Poziotinib CAS 1208243-50-8
Introduction
Product Name: Cibinetide
Other Name :ARA-290
(Cibinetide);ARA290, >98%;ARA290,Cibinetide;Poziotinib;ARA-290(Cibinetide) acetate
CAS NO: 1208243-50-8
Purity: 99%min
Appearance:White Powder
Molecular formula: C51H84N16O21
MW:1257.31
Density :1.56±0.1 g/cm3(Predicted)
Acidity Coefficient (pKa):2.90±0.10
Storage:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
What is Cibinetide?
Cibinetide is a first-in-class synthetic peptide designed to activate innate repair mechanisms in the setting of tissue injury as a result of the inflammatory cascade. It selectively binds to the Innate Repair Receptor (IRR) which activates tissue protective, reparative, and anti-inflammatory signaling pathways.
ARA-290 is a peptide that is derived from e rythropoietin (EPO). EPO has been utilized for decades because of its ability to stimulate red blood cell production within bone marrow. It can also alter a patient's blood pressure, promote cell survival, and create a neuroprotective effect.
While ARA-290 does not stimulate red blood cell production, it does offer pain-relieving and neuroprotective effects.
It also has the potential to stimulate wound repair in patients with chronic diabetes, but this property is still being researched.
ARA-290 is being studied as a potential treatment for systemic lupus erythematosus, as well.
Aplication & Function
The full scope of ARA-290s benefits is still being researched. However, it has the potential to decrease the user's inflammatory pathways through a process known as paracrine signaling. It has also been linked to reduced HbA1c and improved cholesterol numbers. Studies that have produced these results are still in the trial stages.
Perhaps the most appealing possibility for ARA-290 is that it may have the ability to reduce neuropathic symptoms and stimulate natural wound repair processes.
This peptide serves as an exciting treatment option for patients that are dealing with chronic neuropathic pain and diabetes-related ailments.