Chloramphenicol, also known as chloramphenicol, is a broad-spectrum antibiotic that is produced by Streptomyces chlorans and has the effect of inhibiting bacterial growth. The synthetic product is white or yellowish needle-like or flaky crystal, odorless, extremely bitter in taste, slightly soluble in water, ether and chloroform, easily soluble in methanol, alcohol, acetone or ethyl acetate, insoluble in benzene and petroleum ether. It is relatively stable in neutral or weakly acidic aqueous solution, and it is easy to fail in case of alkali. The synthetic product is a racemate, also known as synthomycin. Synthomycin is a mixture of the L- and D-form of chloramphenicol. Because dextrorotate has no antibacterial effect, the efficacy of synthomycin is only half of that of natural products.
Specifications
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Density: 1.6±0.1 g/cm3
Boiling point: 563.2±60.0 °C at 760 mmHg
Melting point: 148-150 °C(lit.)
Molecular formula: C11H12Cl2N2O5
Molecular weight: 323.129
Flash point: 294.4±32.9 °C
Exact Mass: 322.012329
PSA: 115.38000
LogP: 1.62
Appearance: White to off-white crystalline powder
Vapor Pressure : 0.0±1.6 mmHg at 25°C
Refractive index: 1.623
Storage conditions: This product should be sealed and stored in a cool, dark place away from light.