1. Materials information
| Name | Chelidamic acid |
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| Synonym | More Synonyms |
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chelidamic acid Biological Activity
| Description | Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid has good coordination ability with noble metal ions. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM. |
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| Related Catalog | Signaling Pathways >> Others >> Others Research Areas >> Others |
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| Target | Ki: 33 μM (Glutamate decarboxylase)[3]. |
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| In Vitro | Chelidamic acid is a heterocyclic organic acid with a pyran skeleton[1]. Chelidamic acid has good coordination ability with noble metal ions[2]. Chelidamic acid is also one of the most potent inhibitors of glutamate decarboxylase, with a Ki of 33 μM[3]. |
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| References | [1]. Searcey M, et al. Synthesis, DNA-cleaving properties and cytotoxicity of intercalating chelidamic acid derivatives. Anticancer Drug Des. 13(8):837-55. [2]. Espinet P, et al. Mesogenic palladium complexes with pincer ligands derived from dipicolinic acid. Inorg Chem. 2000 Aug, 7;39(16):3645-51. [3]. Porter TG, et al. Chelidonic acid and other conformationally restricted substrate analogues as inhibitors of rat brain glutamate decarboxylase. Biochem Pharmacol. 1985 Dec 1;34(23):4145-50. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 428.3±45.0 °C at 760 mmHg |
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| Melting Point | 267 °C (dec.)(lit.) |
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| Molecular Formula | C7H5NO5 |
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| Molecular Weight | 183.118 |
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| Flash Point | 212.8±28.7 °C |
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| Exact Mass | 183.016769 |
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| PSA | 107.46000 |
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| LogP | -1.43 |
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| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
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| Index of Refraction | 1.635 |
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2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
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Suitable for goods under 50kg
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Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
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Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
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