Product name: Cetirizine hydrochloride
CAS No.: 83881-52-1
Molecular formula: C21H26Cl2N2O3
Molecular weight: 425.35
Melting point: 110-115°C
Cetirizine hydrochloride is a metabolite of hydroxyzine in the human body. Animal experiments have proved that cetirizine hydrochloride is a peripheral H1 receptor antagonist, which can inhibit the transmission and effect of histamine, and can also inhibit the vasoactivity involved in allergic reactions. Peptides and substance P reduce the movement of inflammatory cells and effectively inhibit skin allergies. This product can significantly reduce the tracheal allergic reaction caused by histamine to asthma patients, and reduce the allergic reaction caused by specific allergens. This product has no obvious anticholinergic and antiserotonin effects. In clinical studies, it was found that a more common side effect of cetirizine hydrochloride than placebo is dry mouth. In vitro receptor binding studies have proved that this product has no significant affinity with other H1 receptors. At an effective dose, this product does not easily pass through the blood-brain barrier, and will not affect the central nervous system and cause side effects.
Application
This product is suitable for allergic diseases of the respiratory system, skin and eyes, including perennial allergic diseases, such as allergic skin diseases, measles, allergic rhinitis, eye itching, conjunctivitis and asthma. This product is also used to treat various types of dermatological allergic diseases. Such as the treatment of chronic, artificial, cold, delayed stress, solar measles and atopic dermatitis. This product is also an effective medicine for rapid onset wind masses and quick onset mounds and itching caused by mosquito bites.
China
