Cefpodoxime Proxetil NEW

Cefpodoxime Proxetil: Concise Overview

Definition
Cefpodoxime Proxetil is a third-generation oral cephalosporin antibiotic, classified as a β-lactam prodrug. It is metabolized into its active form, cefpodoxime, which inhibits bacterial cell wall synthesis, targeting a broad spectrum of pathogens.

Function
This antibiotic demonstrates potent bactericidal activity against both Gram-positive and Gram-negative bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and E. coli. It exhibits enhanced stability against certain β-lactamases compared to earlier cephalosporins.

Applications
Cefpodoxime Proxetil is widely prescribed for outpatient and clinical use to treat:

· Respiratory tract infections (e.g., bronchitis, sinusitis, pneumonia)

· Skin and soft tissue infections

· Urinary tract infections (uncomplicated)

· Otitis media (pediatric use)

Its oral bioavailability and once/twice-daily dosing make it ideal for community-acquired infections. Suitable for integration into formulary lists for pharmacies, distributors, and healthcare facilities prioritizing patient compliance and efficacy.