Cefotiam inhibits final cross-linking stage of peptidoglycan production, thus inhibiting
bacterial cell wall synthesis. It has similar or less activity against Gram-positive staphylococci and streptococci, but is resistant to some beta-lactamases produced by Gram-negative bacteria. It is more active against many of the Enterobacteriaceae including Enterobacter,E. coli, Klebsiella, Salmonella and indole-positive Proteus species.
For adults, the dose is up to 6 grams daily by intravenous or intramuscular route in divided doses according to severity of infection. In patients with renal impairment a dose reduction may be needed.
Function:
Mainly used for sensitive to this product are Staphylococcus, Streptococcus (except for bacteria), pneumococcus, influenza bacilli, Escherichia coli, Klebsiella, intestinal bacteria,Citrobacter, Proteus mirabilis , Proteus vulgaris, Proteus vulgaris, Proteus proteus, etc. The following infections: sepsis, postoperative infection, burn infection, subcutaneous abscess,bloated, boil, boil, osteomyelitis, septic arthritis, tonsillitis , Bronchitis, bronchodilation with infection, pneumonia, pulmonary suppuration, empyema, cholangitis, cholecystitis, peritonitis,pyelonephritis, cystitis, urethritis, prostatitis, meningitis, endometritis, pelvic Inflammation,parapneumonitis, annex inflammation, vestibular mastitis, otitis media, sinusitis. 
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