| CAS: | 56796-20-4 |
| MF: | C15H17N7O5S3 |
| MW: | 471.53 |
| EINECS: | 260-384-2 |
| Product Categories: | Pharmaceuticals;Sulfur & Selenium Compounds;Chiral Reagents;Heterocycles;Pharmaceutical intermediate;Medicine intermediate;Intermediates & Fine Chemicals |
| Mol File: | 56796-20-4.mol |
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| Cefmetazole Chemical Properties |
| Melting point | 163-165?C |
| density | 1.4380 (rough estimate) |
| refractive index | 1.7400 (estimate) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly, Heated) |
| pka | 2.65±0.50(Predicted) |
| form | Solid |
| color | White |
| Water Solubility | Soluble in water |
| CAS DataBase Reference | 56796-20-4(CAS DataBase Reference) |
| Cefmetazole Usage And Synthesis |
| Description | Cefmetazole is a cephamycin with a nonaromatic side chain at C-7. In addition to a fairly characteristic second-generation cephalosporin antimicrobial spectrum, it possess fairly significant anti-antiaerobic activity. The ejection of its C-3 side chain leads to alcohol intolerance of the disulfuram type and prolonged clotting times. |
| Chemical Properties | White Solid |
| Uses | Semi-synthetic antibiotic derived from Cephamycin. Antibacterial. |
| Uses | A broad spectrum second generation cephalosporin antibiotic |
| Definition | ChEBI: A cephalosporin antibiotic containg an N1-methyltetrazol-5-ylthiomethyl side-chain at C-3 of the parent cephem bicyclic structure. |
| Antimicrobial activity | It is active against Pr. mirabilis, Pr. vulgaris, Morganella morganii, Yersinia spp.and most anaerobes. S. marcescens is moderately susceptible, but Ps. aeruginosa and E. faecalis are resistant. It is active against Mycobacterium fortuitum and some strains of M. chelonei. It is resistant to a wide range of β-lactamases.
The serum concentration at the end of a 1 g intravenous infusion is around 77 mg/L. Plasma protein binding is 68%. It is principally excreted in the urine with a plasma half-life of c. 1.3 h; 70% is recovered over the first 6 h. In patients whose creatinine clearance is less than 10 mL/min, plasma levels are elevated and the plasma half-life is increased to around 15 h.
Side effects associated with the methylthiotetrazole group at position C-3 have been reported. Uses are similar to those of cefoxitin, but it is not widely available. |
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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In stock
Japan
