### BERBERINE ACID SULFATE: Product Overview
**Definition**
Berberine Acid Sulfate, also known as Berberine Hydrogen Sulphate, is an isoquinoline alkaloid derived from natural sources such as the roots and rhizomes of *Berberis* species. Its chemical formula is C₂₀H₁₉NO₈S, and it is characterized by its yellow crystalline powder form with high solubility in organic solvents like DMSO and chloroform.
**Function**
Berberine Acid Sulfate exhibits multiple pharmacological properties, including:
- **Antimicrobial Activity**: Effective against bacterial and fungal infections by inhibiting DNA topoisomerase and inducing reactive oxygen species (ROS) generation.
- **Antitumor Effects**: Inhibits cancer cell proliferation and induces cell cycle arrest, particularly in colorectal cancer cells.
- **Anti-inflammatory and Neuroprotective Effects**: Reduces inflammation by suppressing TNF-α and protects neurons by activating the PI3K/Akt signaling pathway.
**Applications**
1. **Pharmaceuticals**: Used in the formulation of antimalarial, antibacterial, and anticancer drugs.
2. **Healthcare**: Applied in metabolic disorder treatments, such as diabetes, by improving insulin sensitivity and lipid metabolism.
3. **Research**: Utilized in biochemical studies for its chemopreventive and therapeutic properties.
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