ffective Anti-estrogen Anastrozole Cancer Treatment Steroids Legal Arimidex for Breast Cancer CAS 120511-73-1
Quick Detail :
Product name: Anastrozole
Alias: Arimidex
CAS : 120511-73-1
Molecular formula: C17H19N5
Molecular weight : 293.37
Appearance White crystalline powder
Assay: 98% min
Usage:Treating certain types of breast cancer in women who have been through menopause, including women with disease progression after tamoxifen therapy.
Keywords:Anastrozole ,Arimidex , Anti-estrogen
Description :
Anastrozole is used to treat breast cancer in women who have gone through "the change of life" (menopause). Anastrozole works by lowering estrogen hormone levels to help shrink tumors and slow their growth.
Anastrozole is prescribed for hormone receptor-positive, early breast cancer in postmenopausal women as adjuvant treatment ( treatment following surgery with or without radiation ). Anastrozole is prescribed as a first-line treatment for hormone receptor-positive or hormone receptor unknown, locally advanced or metastatic breast cancer in postmenopausal women. Anastrozole is also prescribed for the treatment of advanced breast cancer in postmenopausal women with disease progression following treatment with tamoxifen.Anastrozole should not be used with tamoxifen because tamoxifen can reduce anastrozole levels in the body and decrease its therapeutic effects.
Applications :
Anastrozole is an aromatase inhibitor, an anti-cancer medication use for the adjuvant or initial treatment of breast cancer in post-menopausal women. Estrogen causes or increases growth of certain breast cancers. Anastrozole works by blocking aromatase enzyme, which is involved in estrogen production in the body. This leads to decreased tumor size or delayed progression of tumor growth in some women. The FDA approved brand name anastrozole (Arimidex) in 1995.
The recommended dose of anastrozole is one tablet (1 mg) by mouth once daily.
Specifications:
Product name | Anastrozole |
Other Name | Arimidex |
Molecular formula | C17H19N5 |
Molecular weight | 293.37 |
Appearance | White crystalline powder |
Identification | IR HPLC Reactive | Conform with standard IR Conform with standard HPLC Conform |
Solubility | Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.16% |
Total Unspecified Impurity | max. 0.2% | 0.06% |
Individual unspecified impurlty | max. 0.1% | 0.06% |
Related compound B | max. 0.2% | 0.06% |
Related compound C | max. 0.2% | 0.05% |
Related compound D | max. 0.1% | 0.06% |
Related compound E | max. 0.1% | 0.05% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0°C | 82.5~83.2°C |
Water | max. 0.3% | 0.23% |
Residue on ignition | max. 0.1% | 0.08% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%~102.0% | 98.9% |
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