Factory Provide 99% Ampicillin Sodium Powder CAS 69-52-3 with Best Price
Introduction
Product Name: Ampicillin Sodium
Other Name :D-6-(-Amino-phenylacetamido)penicillanicacidsodiumsalt;Domicillin
CAS NO:69-52-3
Purity: 99%min
Appearance:White Powder
MF:C16H20N3NaO4S
MW:373.4
Melting Point :215 °C (dec.)(lit.)
Solubility :Freely soluble in water. Sparingly soluble in acetone
Storage:Sealed in dry,Store in 2-8°C
Ampicillin sodium is a broad-spectrum penicillin, its antibacterial spectrum is broader than penicillin , it has antibacterial activity on some gram-negative bacteria (such as Haemophilus influenzae, Escherichia coli, Proteus mirabilis) . Its effects on gram-positive cocci are similar to penicillin. Enzymatic hydrolysis of penicillin produced by bacteria may also make it inactive. It is clinically applicable in the treatment of respiratory infections, urinary tract infections, gastrointestinal tract infections, skin and soft tissue infections, meningitis, septicemia, endocarditis caused by sensitive bacteria. This product is a drug of choice for enterococcal infections.
| Items | Specification | Test Results |
| Characteristic | A white crystalline powder | A white crystalline powder |
| Identification | Conforms | Conforms |
| Assay(on the anhydrous substance) | 96.0%~100.5% | 98.50% |
| Water | 12.0%--15.0% | 13.30% |
| Appearance of solution | ≤2 | 0.5 |
| PH | 3.5~5.5 | 4.40 |
| Specific optical rotation | +280°~ +305° | +300.0° |
| Sulphated ash | ≤0.5% | 0.09% |
| Related substances | ≤1.0% | 0.35% |
Function & Application
1. For the treatment of sensitive enterococci, Shigella, Salmonella, E. coli, Listeria, aerogenes, Haemophilus influenzae and Proteus mirabilis.
2. Broad-spectrum semi-synthetic penicillin drugs, low toxicity. Similar antibacterial spectrum and penicillin, penicillin-sensitive bacteria lower potency, antibacterial effect viridans with penicillin similar or slightly stronger. Against diphtheria, tetanus, and actinomycetes its effectiveness and penicillin basically the same. Enterococcus and Listeria effect is better than benzylpenicillin. And it can produce drug-resistant staph bacteria penicillin had no antibacterial effect. Effective against gram-negative bacteria, but easy to produce drug resistance.
3. Mainly caused by susceptible strains of the drug for urinary system, respiratory system, biliary tract, intestinal infections and meningitis, endocarditis.
4. Mainly used for typhoid, paratyphoid treatment; also for the urinary tract, respiratory tract infections.
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