| Chemical Properties | Colorless liquid |
| Chemical Properties | Allyl bromide is a clear to light yellow liquid. As an alkylating agent, allyl bromide is used extensively in the synthesis of polymers, pharmaceuticals, allyls, and other organic compounds. Allyl bromide is a clear liquid with an intense, acrid, persistent smell and is flammable. It is insoluble in water, but soluble in alcohol, aether, acetone, carbon tetrachloride, and chloroform. In fact, allyl bromide is used in the synthesis of other allyl compounds, to synthesize dyestuff, spice, and as a curative in the medicine industry. Allyl bromide has a very high mobility in soil. It is also used as a soil fumigant and as a contact poison. Allyl bromide induces unscheduled DNA synthesis in HeLa cells. |
| Chemical Properties | Allyl bromide is a highly flammable, colorless to light yellow liquid with an unpleasant, pungent odor. |
| Uses | Allyl Bromide is used as a reagent in the synthesis of Resveratrol derivatives. Resveratrol (R150000) is a minor constituent of wine, correlated with serum lipid reduction and inhibition of platelet a ggregation. Resveratrol is a specific inhibitor of COX-1, and it also inhibits the hydroperoxidase activity of COX-1. It has been shown to inhibit events associated with tumor initiation, promotion a nd progression. |
| Uses | manufacture of synthetic perfumes, other allyl compounds. |
| Uses | Allyl bromide is used as an alkylating agent in the synthesis of pharmaceuticals, polymers, adhesives, perfumes, biochemicals and other allylic compounds. It is used as precursor for the preparation of allyliczinc bromide by reacting it with zinc. It is also used in the preparation of allylethers like allyl decyl ether, allyl benzyl ether and allyl geranyl ether. It is also used in the preparation of R enantiomer of allyl phenyl carbinol (APC) such as 1-phenyl-3-butene, which is a valuable intermediate for drugs and agro-chemicals. |
| General Description | A clear colorless to light yellow liquid with an irritating unpleasant odor. Flash point 30°F. Irritates eyes, skin, and respiratory system. Toxic by skin absorption. Denser than water and slightly soluble in water. |
| Air & Water Reactions | Highly flammable. Slightly soluble in water. |
| Reactivity Profile | Allyl bromide decomposes upon heating and exposure to light, forming HBr (a strong reducing agent). Reacts violently with oxidizing agents. Can react exothermically with reducing agents to release hydrogen gas. In the presence of various catalysts (such as acids) or initiators, may undergo exothermic addition polymerization reactions. |
| Hazard | Strong irritant to skin and eyes, flammable, high fire risk. Upper respiratory tract irritant. Ques- tionable carcinogen. |
| Health Hazard | Inhalation of vapor irritates mucous membranes and causes dizziness, headache, and lung irritation. Contact with liquid irritates eyes and skin. Ingestion causes irritation of mouth and stomach. |
| Health Hazard | Exposures to allyl bromide cause severe eye and skin burns, irritation to the eyes, skin, and respiratory system. It is harmful when absorbed through the skin or inhaled in the workplace. Laboratory rats exposed for a prolonged period of time developed symptoms of poisoning, such as excessive salivation in a small number of animals, and severe gastric irritation. Vapors of allyl bromide may cause dizziness or suffocation, headache, coughing, and distressed breathing. |
| Flammability and Explosibility | Highlyflammable |
| Safety Profile | Poison by ingestion and intraperitoneal routes. Mdly toxic by inhalation. Human mutation data reported. See also ALLYL CHLORIDE and ALLYL COMPOUNDS. Dangerous fire and explosion hazard when exposed to heat, flame, or oxidizers. When heated to decomposition it emits toxic fumes of Br-. To fight fire, use alcohol foam, water spray or mist, CO2, dry chemical |
| Synthesis | Allyl alcohol was synthesized from glycerol and formic acid under inert atmosphere, hydrolysed with NaOH and fractionally distilled to yield the 73% allyl alcohol water azeotrope. This was then reacted with 48% hydrobromic acid and sulfuric acid and the allyl bromide distilled as per the conventional method. It was then redistilled with 3A molecular sieves drying agent to yield the final product which is stored over additional 3A molecular sieves. |
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