Name | AA26-9 |
Description | AA26-9 is an effective and broad-spectrum inhibitor of serine hydrolase. |
Cell Research | AA26-9 is prepared in DMSO. Cells are cultured with 20 μM inhibitor AA26-9 or DMSO as a control for 4 h, lysed, separated into soluble and analyzed by competitive gel-based ABPP[1]. |
In vitro | AA26-9 inhibits enzymes originated from diverse functional subclasses of serine hydrolases, including peptidases (APEH, CTSA, PRCP), thioesterases (LYPLA1/2), lipases/phospholipases (AADACL1, ESD, ABHD6, PAFAH2, FAAH, LYPLA3), and uncharacterized enzymes (ABHD11, ABHD13, BAT5). AA26-9 inhibits 1/3 of the over 40 serine hydrolase found in T-cells. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 55 mg/mL (330.96 mM)
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Keywords | peptidases | thioesterases | Phospholipase | AA269 | serine | esterases | AA-26-9 | AA26 9 | Inhibitor | lipases | amidases | inhibit | AA26-9 | cell |
Inhibitors Related | Neomycin sulfate | 1-Naphthaleneacetic acid potassium salt | trans-Benzylideneacetone | PMSF | Nafamostat mesylate | Benzylideneacetone | AEBSF hydrochloride | Indomethacin | 1-Naphthaleneacetic acid | Darapladib | Lansoprazole | Benzamidine hydrochloride |
Related Compound Libraries | Bioactive Compound Library | Anti-Obesity Compound Library | Protease Inhibitor Library | Inhibitor Library | NO PAINS Compound Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |