Product Name: N-Methyl-N-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine
Synonyms: BUTENAFINE;n-methyl-n-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine;n-(p-tert-butylbenzyl)-n-methyl-1-naphthalenemethylamine;N-methyl-N-(4-methylbenzyl)-N-(1-naphthylmethyl)amine;4-tert-Butylbenzylmethyl 1-naphtylmethylamine;N-(4-tert-Butylbenzyl)-N-methyl-1-naphthalenemethanamine;(4-tert-butylbenzyl)-methyl-(1-naphthylmethyl)amine;1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine
CAS: 101828-21-1
MF: C23H27N
MW: 317.47
EINECS:
Product Categories:
Mol File: 101828-21-1.mol
N-Methyl-N-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine Structure
N-Methyl-N-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine Chemical Properties
Melting point 200-202 °C
Boiling point 426.1±14.0 °C(Predicted)
density 1.032±0.06 g/cm3(Predicted)
pka 7.87±0.50(Predicted)
CAS DataBase Reference 101828-21-1(CAS DataBase Reference)
Safety Information
MSDS Information
N-Methyl-N-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine Usage And Synthesis
Uses Antifungal.
Definition ChEBI: Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in funga cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
Brand name Lotrimin (Schering); Mentax (Mylan Bertek).
N-Methyl-N-(naphthalen-1-ylmethyl)-1-(4-tert-butylphenyl)methanamine Preparation Products And Raw materials
China
