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ChemicalBook Product Catalog Biochemical Engineering Inhibitors Mitogen-activated protein kinase (MAPK) p38 MAPK inhibitor LY2228820

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LY2228820

$ 1.00 /1g

Min. Order1g
Purity99%
Cas No862507-23-1
Supply Ability200kg
Update time2020-01-13

career henan chemical co

5YR

China

Since2014-12-17

AddressRoom 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H

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Chemical Properties

Product Name	LY2228820
CAS No	862507-23-1
EC-No
Min. Order	1g
Purity	99%
Supply Ability	200kg
Release date	2020/01/13

Mary

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Product Name:

LY2228820

Synonyms:

Ralimetinib 2MsOH(LY2228820);LY2228820;5-[2-(1,1-DiMethylethyl)-5-(4-fluorophenyl)-1H-iMidazol-4-yl]-3-(2,2-diMethylpropyl)-3H-iMidazo[4,5-b]pyridin-2-aMine DiMethanesulfonate;LY2228820(LY-2228820);LY2228820 2MsOH;LY2228820 diMesylate;5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate;5-(2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate

CAS:

862507-23-1

MF:

C26H37FN6O6S2

MW:

612.7369832

EINECS:

Product Categories:

Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Inhibitors;MAPK

Mol File:

862507-23-1.mol

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LY2228820 Chemical Properties

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Safety Information

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MSDS Information

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LY2228820 Usage And Synthesis

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Uses

LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events.

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LY2228820 Preparation Products And Raw materials

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Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

LY2228820

Company Profile Introduction

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