Product Name: DAPT
Synonyms: γ-Secretase Inhibitor IX - CAS 208255-80-5 - Calbiochem;(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester;LY-374973, N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-S-phenylglycine t-butyl ester;γ-Secretase Inhibitor IX;N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethylester;SC-201315;(2S)-N-[N-(3,5-Difluorophenacetyl)-L-alanyl]-2-phenylglycine tert-butyl ester;DAPT (enzyme inhibitor)
CAS: 208255-80-5
MF: C23H26F2N2O4
MW: 432.464
EINECS:
Product Categories: -;Angiogenesis and Metastasis;Protease inhibitor;Inhibitor;GSI-IX;Inhibitors
Mol File: 208255-80-5.mol
DAPT Structure
DAPT Chemical Properties
alpha +40.0～+47.0°(D/20℃)(c=0.5,DMSO)
Boiling point 612.2±55.0 °C(Predicted)
density 1.213
storage temp. 2-8°C
solubility DMSO: ~18 mg/mL
pka 12.82±0.46(Predicted)
form solid
color white
Sensitive Light Sensitive
InChIKey DWJXYEABWRJFSP-XOBRGWDASA-N
CAS DataBase Reference 208255-80-5
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29242990
MSDS Information
DAPT Usage And Synthesis
Uses DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells
Uses A potent and specific inhibitor of γ-secretase.
China
