Product Name: Halobetasol propionate
Synonyms: 21-chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate;6 alpha-fluoroclobetasol 17-propionate;(6α，11β，16β)-21-Chloro-6，9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1，4-diene-3，20-dione;BMY-30056;CGP-14458;Uiobetasol Propionate;Ultravate;Pregna-1,4-diene-3,20-dione, 21-chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (6-alpha,11-beta,16-beta)
CAS: 66852-54-8
MF: C25H31ClF2O5
MW: 484.96
EINECS: 686-247-0
Product Categories: Steroids;Inhibitors
Mol File: 66852-54-8.mol
Halobetasol propionate Structure
Halobetasol propionate Chemical Properties
Melting point 213-215°C
Boiling point 570.7±50.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
storage temp. Refrigerator
pka 12.55±0.70(Predicted)
CAS DataBase Reference 66852-54-8(CAS DataBase Reference)
Safety Information
HS Code 2937220000
MSDS Information
Provider Language
Ulobetasol propionate English
Halobetasol propionate Usage And Synthesis
Description Halobetasol propionate is a new ultra-potent topical corticosteroid exhibiting both antiinflammatory and antihyperplasia properties. The compound is recommended for the treatment of moderate to severe corticosteroid-responsive dermatoses and appears to be particularly effective in patients with plaque psoriasis.
Chemical Properties White Solid
Originator Ciba-Geigy (Switzerland)
Uses Anti-inflammatory; a dermatologic agent commonly used to treat psoriasis
Brand name Ultravate (Westwood-Squibb).
Halobetasol propionate Preparation Products And Raw materials
Raw materials Methanesulfonyl chloride-->Lithium chloride-->Acetylacetone
China
