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ChemicalBook Product Catalog Motesanib

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Motesanib

$ 1.00 /1g

Min. Order1g
Purity99%
Cas No453562-69-1
Supply Ability100kgs
Update time2020-01-03

career henan chemical co

5YR

China

Since2014-12-17

AddressRoom 702, Floor 7, Building 10, National University Science Park, High-Tech Zone, Zhengzhou City, H

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Chemical Properties

Product Name	Motesanib
CAS No	453562-69-1
EC-No
Min. Order	1g
Purity	99%
Supply Ability	100kgs
Release date	2020/01/03

Mary

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Product Name:

Motesanib

Synonyms:

N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide;3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-;Motesanib Base;AMG-706(Motesanib);Motesanib (AMG-706) Base);motesanib;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706

CAS:

453562-69-1

MF:

C22H23N5O

MW:

373.45

EINECS:

Product Categories:

Antineoplastic;Inhibitors;API

Mol File:

453562-69-1.mol

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Motesanib Chemical Properties

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Boiling point

517.3±50.0 °C(Predicted)

density

1.251

form

White powder solid.

pka

11.75±0.40(Predicted)

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Safety Information

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MSDS Information

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Motesanib Usage And Synthesis

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Chemical Properties

Pale Yellow Solid

Uses

Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.

Uses

Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.

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Motesanib Preparation Products And Raw materials

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Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates： Pharmaceutical intermediates; OLED intermediates;

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