Phenyl carbamate

▼

▲

Phenyl carbamate Basic information

▼

▲

Product Name:

Phenyl carbamate

Synonyms:

PHENYL CARBAMATE;Phenylcarbamate,98+%;CARBAMICACID,PHENYLESTER;o-Phenyl carbamate;Phenyl carbamate,97%;Phenyl carbaMate 97%

CAS:

622-46-8

MF:

C7H7NO2

MW:

137.14

EINECS:

210-737-1

Product Categories:

Nitrogen Compounds;Organic Building Blocks;Protected Amines

Mol File:

622-46-8.mol

▼

▲

Phenyl carbamate Chemical Properties

▼

▲

Melting point

149-152 °C(lit.)

Boiling point

251.96°C (rough estimate)

density

1.2528 (rough estimate)

refractive index

1.5030 (estimate)

pka

12.33±0.50(Predicted)

Water Solubility

Soluble in water.

BRN

2042627

CAS DataBase Reference

622-46-8(CAS DataBase Reference)

▼

▲

Phenyl carbamate Usage And Synthesis

▼

▲

Chemical Properties

white to very slightly pink crystalline flakes

Uses

Phenyl carbamate is used as various phenyl carbamate esters derived from amino acids, a dipeptide and amino acid esters and amides were prepared and assessed as potential prodrugs with the aim of protecting phenolic drugs against first-pass metabolism following per oral administration.

A tin-catalyzed transcarbamoylation of primary and secondary alcohols with phenyl carbamate proceeds smoothly in toluene at 90℃ to generate the corresponding carbamates in good yields. This mild method exhibits a broad functional-group tolerance.
Y. Ichikawa, Y. Morishita, S. Kusaba, N. Sakiyama, Y. Matsuda, K. Nakano, H. Kotsuki, Synlett, 2010, 1815-1818.
http://dx.doi.org/10.1055/s-0030-1258102

Product Name	Phenyl carbamate
CAS No	622-46-8
EC-No	200-528-9
Min. Order	1KG
Purity	95-99%
Supply Ability	1ton
Release date	2020/01/01

Company Profile Introduction

You may like

Recommended supplier