Product Name: Hydrocortisone 21-hemisuccinate
Synonyms: cortisolsuccinate;hydrocortisone21-succinate;saxizon;(11-beta)-21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxypreg-4-ene-3,20-dione;17-dihydroxy-20-dion(11-beta)-preg-4-ene-21-(3-carboxy-1-oxopropoxy)-11;cortisol,21-(hydrogensuccinate);cortisol,hydrogensuccinate;11beta,17,21-Trihydroxypregn-4-ene-3,20-dione21-(hydrogensuccinate)
CAS: 2203-97-6
MF: C25H34O8
MW: 462.53
EINECS: 218-612-3
Product Categories: Steroid and Hormone;Steroids
Mol File: 2203-97-6.mol
Hydrocortisone 21-hemisuccinate Structure
Hydrocortisone 21-hemisuccinate Chemical Properties
Melting point 170～172℃
alpha [α]D20 +147～+153° (c=1, C2H5OH) (After Drying)
Boiling point 685.5±55.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
storage temp. −20°C
solubility Practically insoluble in water, freely soluble in acetone and in anhydrous ethanol. It dissolves in dilute solutions of alkali carbonates and alkali hydroxides.
pka pKa 5.10/5.64(20% aq EtOH/50% aq EtOH) (Uncertain)
form neat
Safety Information
Safety Statements 22-24/25
WGK Germany 3
RTECS TU5010147
MSDS Information
Provider Language
SigmaAldrich English
Hydrocortisone 21-hemisuccinate Usage And Synthesis
Chemical Properties White or almost white, hygroscopic powder
Uses glucocorticoid
Definition ChEBI: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).
Brand name A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).
Hydrocortisone 21-hemisuccinate Preparation Products And Raw materials
China
