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PUROMYCINAMINONUCLEOSIDE

$ 1.00 /1KG

Min. Order1KG
Purity99%
Cas No58-60-6
Update time2019-12-20

career henan chemical co

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China

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Chemical Properties

Product Name	PUROMYCINAMINONUCLEOSIDE
CAS No	58-60-6
EC-No	200-388-3
Min. Order	1KG
Purity	99%
Release date	2019/12/20

heidi60

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Product Name:

PUROMYCIN AMINONUCLEOSIDE

Synonyms:

3'-AMINO-3'-DEOXY-N6,N6-DIMETHYLADENOSINE;3'-AMINO-3'-DEOXY-N,N-DIMETHYL-ADENOSINE;6-DIMETHYLAMIN-9-[3'-AMINO-3'DEOXYRIBOSYL]-PURINE;Puromycin Aminonucleoside, 6-Dimethylamin-9-[3-amino-3deoxyribosyl]-purine;9-(3-Amino-3-deoxy-.beta.-D-ribofuranosyl)-N,N-dimethyl-9H-purin-6-amine;Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl-;Aids000507;Aids-000507

CAS:

58-60-6

MF:

C12H18N6O3

MW:

294.31

EINECS:

200-388-3

Product Categories:

Mol File:

58-60-6.mol

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PUROMYCIN AMINONUCLEOSIDE Chemical Properties

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Melting point

235℃ (Decomposition)

Boiling point

436.08°C (rough estimate)

density

1.2131 (rough estimate)

refractive index

1.7000 (estimate)

>110°(230°F)

storage temp.

2-8°C

solubility

H₂O: 50 mg/mL, clear, slightly yellow

form

liquid

pka

13.26±0.70(Predicted)

Water Solubility

Soluble in water at 50mg/ml. May require heating

BRN

93902

InChIKey

RYSMHWILUNYBFW-GRIPGOBMSA-N

EPA Substance Registry System

Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl- (58-60-6)

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Chemical Properties

White crystal

Uses

Puromycin aminonucleoside is a semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis, but exhibits antitumour properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing integrin expression in cultured glomerular epithelial cells.

Uses

Puromycin aminonucleoside is a semi-synthetic derivative of puromycin which lacks the methoxyphenylalanyl moiety. Puromycin aminonucleoside is the key intermediate in the synthesis of semi-synthetic analogues of puromycin. It does not inhibit protein synthesis or induce apoptosis, but exhibits antitumor properties. Puromycin aminonucleoside-induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, suppressing integrin expression in cultured glomerular epithelial cells.

Definition

ChEBI: Puromycin derivative that lacks the methoxyphenylalanyl group on the amine of the sugar ring.

Safety Profile

An experimental teratogen. Other experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

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