Quinolinic acid

Product Name:

Quinolinic acid

Synonyms:

2,3-PyridinedicarboxylicAcid99%;QuinolinicAcid>99%;Pyridin-2,3-dicarbonsaeure;2,3-Pyridinedicarboxylic;2,3-PYRIDINEDICARBOXYLIC ACID (QUINOLINIC ACID);2,3-pyridine dicarbo;2,3-PYRIDINEDICARBOXYLIC ACID;AKOS BBS-00003814

CAS:

MF:

C7H5NO4

MW:

167.12

EINECS:

201-874-8

Product Categories:

Medical Intermediates;Pyridine series;Pyridine;pyridine derivative;Carboxylic Acids;Pyridines;-;Heterocyclic Compounds;Heterocycles;Inhibitors;Carboxylic Acids;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Pesticides intermediate;Pyrimidines

Mol File:

89-00-9.mol

 

Quinolinic acid Chemical Properties

Melting point 

188-190 °C (dec.)(lit.)

Boiling point 

295.67°C (rough estimate)

density 

1.5216 (rough estimate)

refractive index 

1.6280 (estimate)

storage temp. 

Store at RT

solubility 

10g/l

pka

2.43(at 25℃)

form 

Crystalline Powder

color 

White to light yellow-beige

Water Solubility 

0.55 g/100 mL

Merck 

14,8073

BRN 

137110

InChIKey

GJAWHXHKYYXBSV-UHFFFAOYSA-N

CAS DataBase Reference

89-00-9(CAS DataBase Reference)

EPA Substance Registry System

2,3-Pyridinedicarboxylic acid(89-00-9)

 

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38-33

Safety Statements 

26-36/37-24/25-37

WGK Germany 

3

RTECS 

US7967250

TSCA 

T

HazardClass 

IRRITANT

HS Code 

29333999

Hazardous Substances Data

89-00-9(Hazardous Substances Data)

MSDS Information

 

Quinolinic acid Usage And Synthesis

Chemical Properties

White powder;Light yellow powder

Uses

Inhibits glucose synthesis

Uses

An inhibitor of glucose synthesis.

Uses

A matabolite of tryptophan and a putative NMDA receptor agonist.

Hazard

A poison by skin contact. Moderately toxic by ingestion. A mild skin irritant.

Industrial uses

The use of quinolinic acid during flotation of hematite results in the adsorption of quinoline on hematite, allowing amine to selectively adsorb onto the hematite surface.

Biological Activity

Endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.

Safety Profile

A poison by skin contact. Moderately toxic by ingestion. Experimental reproductive effects. A mdd skinn irritant. When heated to decomposition it emits toxic vapors of NOx.