6-Carboxyfluorescein

Product Name:

6-Carboxyfluorescein

Synonyms:

2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)terephthalic acid;Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylicacid, 3',6'-dihydroxy-3-oxo-;6-Carboxyfluorescein, Single isomer;3',6'-dihydroxy-3-oxospiro[2-benzofuran-1,9'-xanthene]-6-carboxylic acid;6-FAM;6-CARBOXYFLUORESCEIN;2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-TEREPHTHALIC ACID;6-Carboxyfluorescein (6-FAM)

CAS:

MF:

C21H12O7

MW:

376.32

EINECS:

636-503-2

Product Categories:

Electronic Chemicals;Fluorescent Labels and Indicators;marker;Fluorescent Labels & Indicators;Fluorescent;Xanthene

Mol File:

3301-79-9.mol

 

6-Carboxyfluorescein Chemical Properties

Melting point 

>300 °C(lit.)

storage temp. 

2-8°C

solubility 

DMSO: soluble

form 

Solid

pka

3.3, 4.6, 6.4, 7.0(at 25℃)

color 

Yellow to orange

PH Range

Weak green ' uorescence (6.0) to strong green ' uourescence (7.2)

λmax

492nm

BRN 

54341

Major Application

Diagnosis of hematologic cancer, nongastric diseases, detection of genetically modified wheat, chromosomes, gene expression, nucleic acid, hepatitis A virus, avian influenza virus subtype H5 and H5N1, SARS virus, herpex simplex virus

Biological Applications

Diagnosing bladder cancer; evaluating corneal endothelial barrier function; as a substrate for measuring protein kinase activity, methyltransferase activity, phospholipase activity, rhodanese activity,sulfotransferase activity;use in ophthalmology

CAS DataBase Reference

3301-79-9(CAS DataBase Reference)

EPA Substance Registry System

Spiro[isobenzofuran- 1(3H),9'-[9H]xanthene]- 6-carboxylic acid, 3',6'-dihydroxy- 3-oxo-(3301-79-9)

 

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37

WGK Germany 

3

F 

10-21

HS Code 

3204 90 00