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6-Carboxyfluorescein

Basic information Safety Related Supplier
6-Carboxyfluorescein Basic information
6-Carboxyfluorescein Chemical Properties
  • Melting point:>300 °C(lit.)
  • Boiling point:736.4±60.0 °C(Predicted)
  • Density 1.73±0.1 g/cm3(Predicted)
  • storage temp. Sealed in dry,2-8°C
  • solubility DMSO: soluble
  • pka3.3, 4.6, 6.4, 7.0(at 25℃)
  • form Solid
  • color Yellow to orange
  • PH RangeWeak green ' uorescence (6.0) to strong green ' uourescence (7.2)
  • λmax492nm
  • BRN 54341
  • Major ApplicationDiagnosis of hematologic cancer, nongastric diseases, detection of genetically modified wheat, chromosomes, gene expression, nucleic acid, hepatitis A virus, avian influenza virus subtype H5 and H5N1, SARS virus, herpex simplex virus
  • Biological ApplicationsDiagnosing bladder cancer; evaluating corneal endothelial barrier function; as a substrate for measuring protein kinase activity, methyltransferase activity, phospholipase activity, rhodanese activity,sulfotransferase activity;use in ophthalmology
  • CAS DataBase Reference3301-79-9(CAS DataBase Reference)
  • EPA Substance Registry SystemSpiro[isobenzofuran-1(3H),9'-[9H]xanthene]-6-carboxylic acid, 3',6'-dihydroxy-3-oxo- (3301-79-9)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 26-36/37
  • WGK Germany 3
  • 10-21
  • HS Code 3204 90 00
MSDS
6-Carboxyfluorescein Usage And Synthesis
  • Chemical PropertiesOrange Solid
  • UsesDerivative of fluorescein giving stable derivative upon conjugation with biopolymers.
  • Uses
    6-Carboxyfluorescein has been used to check the plasma membrane integrity in sperm cells.
  • Uses6-Carboxyfluorescein is a useful reagent for the preparation of hydrolytically stable fluorescent conjugates and is a useful starting material for the synthesis of other fluorescein-derives reagent
  • Biochem/physiol Actions6-Carboxyfluorescein diacetate is a membrane permeable compound. It can be hydrolysed by intracellular esterases to form a membrane impermeable bright green fluorescent molecule, 6-carboxyfluorescein.
6-Carboxyfluorescein(3301-79-9)Related Product Information
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