TYRPHOSTIN AG 1024

Product Name:

TYRPHOSTIN AG 1024

Synonyms:

2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile;AGS 200;Tyrphostin;2-[[3-Bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]propanedinitrile AGS 200;HY-10253;AG-1024 (Tyrphostin);AG 1024 - CAS 65678-07-1 - Calbiochem;2-(3-broMo-5-tert-butyl-4-hydroxybenzylidene)Malononitrile

CAS:

MF:

C14H13BrN2O

MW:

305.174

EINECS:

 

Product Categories:

 

Mol File:

65678-07-1.mol

 

TYRPHOSTIN AG 1024 Chemical Properties

storage temp. 

−20°C

solubility 

DMSO: soluble

form 

solid

color 

yellow

 

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

MSDS Information

 

TYRPHOSTIN AG 1024 Usage And Synthesis

Uses

Specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor kinases. Induces apoptosis by downregulation of the expression of phospho-Akt1 and Bcl-2. Also increases Bax, p53 and p21 expression.