Azosemide

Product Name:

Azosemide

Synonyms:

2-chloro-5-(1h-tetrazol-5-yl)-n(sup4)-2-thenylsulfanilamide;5-(4’-chloro-5’-sulfamoyl-2’-thenylaminophenyl)-tetrazole;azosemid;ple1053;AZOSEMIDE;2-chloro-5-(1h-tetrazol-5-yl)-4-(2-thenylamino)benzenesulphonamide;2-chloro-5-(1h-tetrazol-5-yl)-4-((2-thienylmethyl)amino)-benzenesulfonamid;2-CHLORO-5-(1H-TETRAZOL-5-YL)-4-((2-THIENYLMETHYL)AMINO)-BENZENESULFONAMIDE

CAS:

MF:

C12H11ClN6O2S2

MW:

370.84

EINECS:

248-549-7

Product Categories:

-

Mol File:

27589-33-9.mol

 

Azosemide Chemical Properties

Melting point 

218-221°

Boiling point 

221°C (rough estimate)

density 

1.6843 (rough estimate)

refractive index 

1.6100 (estimate)

CAS DataBase Reference

27589-33-9(CAS DataBase Reference)

Azosemide Usage And Synthesis

Description

Azosemide is a high-ceiling diuretic similiar in structure and profile to furosemide, albeit somewhat less potent and less bioavailable. It is useful in the treatment of congestive heart failure and similar edematous conditions.

Originator

Boehringer Manheim (W. Germany)

Uses

Diuretic.

Definition

ChEBI: A sulfonamide that is benzenesulfonamide which is substituted at positions 2, 4, and 5 by chlorine, (2-thienylmethyl)amino and 1H-tetrazol-5-yl groups, respectively. It is a diuretic that has been used in the management of oedema and hyp rtension.

Brand name

LURET