Cidofovir

Cidofovir Basic information

Product Name:

Cidofovir

Synonyms:

Cidofovir hydrate (1:2);P-[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic acid hydrate (1:2);Cidofovir hydrate;Drg-0145;Gs-0504;Phosphonic acid, ((2-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy)methyl)-, dihydrate, (S)-;(S)-(3-(4-aMino-2-oxopyriMidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)Methylphosphonic acid dihydrate;(S)-[[2-(4-AMino-2-oxo-1(2H)-pyriMidinyl)-1-(hydroxyMethyl)ethoxy]Methyl]phosphonic Acid Hydrate

CAS:

MF:

C8H14N3O6P

MW:

279.187021

EINECS:

814-987-8

Product Categories:

Amines;Anti-virals;Heterocyles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents

Mol File:

149394-66-1.mol

 

Cidofovir Chemical Properties

 

Safety Information

HS Code 

2933599550

MSDS Information

 

Cidofovir Usage And Synthesis

Chemical Properties

White Solid

Uses

An injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefo re prevention of viral replication and transcription. It is used in the treatment of acyclovir resistant herpes as well as a complementary intralesional therapy against papillomatosis caused by human papillomavirus (HPV).

Definition

ChEBI: The dihydrate of the anhydrous form of cidofovir. A nucleoside analogue, it is an injectable antiviral used for the treatment of cytomegalovirus (CMV) retinitis in AIDS patients.

Brand name

Vistide (Gilead Sciences).