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Carbonyl cyanide-4-(trifluoromethoxy)phenylhydrazone (FCCP) is an ionophore that is a mobile ion carrier. It is referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation. It is a nitrile and hydrazone. FCCP was first described in 1962 by Heytler.
Basic Info
Chemical Name |
carbonyl cyanide p-trifluoromethoxyphenylhydrazone |
Synonyms |
2-[[4-(trifluoromethoxy)phenyl]hydrazinylidene]propanedinitrile;FCCP,Mesoxalonitrile 4-trifluoromethoxyphenylhydrazone;Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone;
|
CAS No. |
370-86-5 |
Molecular Formula |
C10H5F3N4O |
Molecular Weight |
254.16800 |
PSA |
81.20000 |
LogP |
2.47326 |
Properties
Appearance & Physical State |
White solid |
Density |
1.34 g/cm3 |
Boiling Point |
293.3ºC at 760 mmHg |
Melting Point |
174-175ºC (dec.)(lit.) |
Flash Point |
131.2ºC |
Refractive Index |
1.522 |
Storage Condition |
2-8ºC |
Safety Info
Hazard Class |
6.1(a) |
Safety Statements |
36/37-45 |
HS Code |
2928000090 |
Packing Group |
II |
RIDADR |
UN 2811 6 |
Risk Statements |
R25 |
Hazard Codes |
T; Xi |
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