Niacin is also called vitamin B3, or vitamin PP, molecular formula: C6H5NO2, heat-resistant, can sublimate. Niacin is also known as niacin and anti-skin disease factor. Also included in the human body is its derivative nicotinamide or nicotinamide. It is one of the 13 kinds of vitamins necessary for the human body. It is a water-soluble vitamin and belongs to the vitamin B family. Niacin is converted into nicotinamide in human body. Niacinamide is a component of coenzyme I and coenzyme II, and participates in the process of lipid metabolism, tissue oxidation and anaerobic decomposition of carbohydrates. [1]
Nicotinic acid and nicotinamide are soluble in water and alcohol; the properties of nicotinic acid and nicotinamide are relatively stable, and are not easily destroyed under acid, alkali, oxygen, light or heating conditions; under high pressure, 120 ° C, 20 min is not destroyed. General processing and cooking losses are small, but they are lost with water.
use
Niacin has a strong effect of dilating peripheral blood vessels and is used clinically for the treatment of headache, migraine, tinnitus, and inner ear vertigo.
Niacin is a vitamin drug, and nicotinamide is collectively called vitamin PP. It is used for anti-pellagra, and can also be used as a blood-swelling drug. It is widely used as an additive for food and feed. As a pharmaceutical intermediate, it is used in the production of isoniazid, nicotinamide, nicotin, and inositol nicotinate.
If it is lacking, it can produce pellagra, which is characterized by dermatitis, glossitis, oropharynx, diarrhea and irritability, and insomnia. Niacin is one of the few vitamins that are relatively stable in food. Even if it is cooked and stored, it will not be lost and its effectiveness will be affected.
Utility: promote the health of the digestive system, reduce gastrointestinal disorders; make the skin healthier; prevent and alleviate severe migraine; promote blood circulation, lower blood pressure; reduce diarrhea.
Introduction to indications:
1. It is used to prevent niacin deficiency such as pellagra. Also used as a vasodilator to treat hyperlipidemia. Also used for the treatment of vascular migraine, headache, cerebral arterial thrombosis, pulmonary embolism, inner ear vertigo, frostbite, central retinal choroiditis.
2, strict control or choice of diet, or patients receiving parenteral nutrition, due to malnutrition, sudden weight loss, pregnancy, lactation, and taking isoniazid, severe addiction, alcohol abuse, drug users, niacin need increased .
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