Description
Product name: Sodium picosulfate
Other Name: 4,4'-(pyridin-2-ylmethylene)bisphenyl bis (sodiumsulphate);sodium picosulfate;Picosulfate Sodium;Disodium bis[4-[(hydroxysulfonyl)oxy]phenyl](2-pyridyl)methane;Evacuol;Laxoberal;Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2);Picolax
Original: China
CAS: 10040-45-6
Molecular formula: C18H13NO8S2.2Na
MW: 481.41
Usage: Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.
COA:
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Product name
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Sodium picosulfate
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Description
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White Or Almost White Crystalline Powder
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White Powder
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Identification
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Infrared Absorption
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Positive
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Assay
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97.0~103.0%
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98.5%
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Melting Point
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33~37° C
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34.5~36.5° C
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Loss On Drying
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0.5%max
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0.25%
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Specific Rotation
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+31° ~ +36° (C=1 in dioxane)
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+33.5°
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Organic Volatile Impurities
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2500PPm max
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< 1000PPm
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Residual Solvents
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Meet the requirements. (USP29)
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Confirms
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Chromatographic purity
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sum of impurities: 3.0%max
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< 3.0%
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Description:
Sodium picosulfate (INN, also known as sodium picosulphate) is a contact stimulant laxative used as a treatment for constipation or to prepare the large bowel before colonoscopy or surgery. It is sold under the trade names Sodipic Picofast, Laxoberal, Laxoberon, Purg-Odan, Picolax, Guttalax, Namilax, Pico-Salax and Prepopik among others. PicoPrep is based on Sodium picosulphate.
Usage:
Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria.
Medical Effect:
1.Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12-24 hours to work, since it works in the colon.
2.The most common side effects of picosulfate are abdominal cramps and diarrhea.
3.The use of sodium picosulfate has also been associated with certainelectrolyte disturbances, such as hyponatremia and hypokalemia. Patients are often required to drink large amounts of clear fluids as well as rehydrate to reestablish the electrolyte balance.
How to Storage?
- It is recommended to store at the room temperature below 30 degrees C.
- Keep the drug away from direct sunlight, heat and moisture.
- Do not let the drug at the sight and reach of children.
China
